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Anisodamine
go.drugbank.com/drugs/DB11785InvestigationalAnisodamine has been investigated for the treatment of Intestinal Diseases.
Categories: Analgesics, Non-NarcoticDelapril
go.drugbank.com/drugs/DB13312InvestigationalCategories: Agents Acting on the Renin-Angiotensin SystemTetrahydropalmatine
go.drugbank.com/drugs/DB12093InvestigationalTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Categories: Analgesics, Non-NarcoticVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalVasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour. Vasopressin is v...
Methadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational[A185876] Compared to other opioids, methadone's effects on NMDA inhibition may explain it's improved analgesic efficacy and reduced opioid tolerance.
Seratrodast
go.drugbank.com/drugs/DB06739ExperimentalSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Categories: Analgesics, Non-NarcoticFimasartan
go.drugbank.com/drugs/DB09279InvestigationalFimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fim...
Categories: Agents Acting on the Renin-Angiotensin SystemNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Categories: Non-Selective Monoamine Reuptake InhibitorsMedical Cannabis
go.drugbank.com/drugs/DB14009Investigationalknown as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a wave of legalization in North America has changed public and medical opinion on … Allosteric regulation is achieved through the modulation of receptor activity on a functionally distinct site from the agonist or antagonist binding site, which is therapeutically important as direct agonists
Gantenerumab
go.drugbank.com/drugs/DB12034InvestigationalAlzheimer's disease (AD) is the most common cause of dementia in elderly patients, with classical histopathological hallmarks including extracellular amyloid-beta (Aβ) plaques and intraneuronal neurofibrillary tangles (NFTs). As the clas...