Search

Displaying results 4041 - 4050 of 10000 in total
  1. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: TALLARME®, OBESTOP® 10 MG CAPSULAS
  2. Drug

    ATN-161

    go.drugbank.com/drugs/DB05491
    Investigational

    It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. … Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor angiogenesis is similar across a range of different cancers, the therapeutic benefit of ATN-161 is

  3. Drug

    Molnupiravir

    go.drugbank.com/drugs/DB15661
    Investigational

    [A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’-triphosphate form. … COVID-19 in adults.

    Categories: Heterocyclic Compounds, 1-RingProducts: LAGEVRIO® 200MG CAPSULAS
  4. Drug

    Pazopanib

    go.drugbank.com/drugs/DB06589
    ApprovedInvestigational

    Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VOTRIENT® 200 MG, VOTRIENT® 400 MG
  5. Drug

    Propyl Gallate

    go.drugbank.com/drugs/DB12450
    Investigational

    Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    2,4-Dinitrophenol

    go.drugbank.com/drugs/DB04528
    Experimental

    It is also used as a metabolic stimulant. (Stedman, 26th ed) … A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    ISS-1018

    go.drugbank.com/drugs/DB05463
    Investigational

    ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. … It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma.

  8. Drug

    Bambusa arundinacea stem

    go.drugbank.com/drugs/DB14588
    Investigational

    Mixtures: Re-action E
  9. Drug

    Maltodextrin

    go.drugbank.com/drugs/DB12583
    Investigational

    Mixtures: Re-action E
  10. Drug

    Chlortetracycline

    go.drugbank.com/drugs/DB09093
    ApprovedVet approvedWithdrawn

    He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. … It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow.

    Mixtures: Aureocort 1 mg/g + 30 mg/g SalbeProducts: Aureomycin Ont 3%, Aureomycin Ont Oph 1%