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Terevalefim
go.drugbank.com/drugs/DB16397InvestigationalTerevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).
Categories: Heterocyclic Compounds, 1-RingCenisertib
go.drugbank.com/drugs/DB06347InvestigationalCenisertib is an aurora kinase inhibitor.
Categories: Heterocyclic Compounds, 1-RingElacytarabine
go.drugbank.com/drugs/DB05494InvestigationalElacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is a patented new chemical entity of the nucleoside analog class, with improved biological properties and the potential to treat solid tumours such as non-small cell lung cancer, malignant
Categories: Heterocyclic Compounds, 1-RingDarusentan
go.drugbank.com/drugs/DB04883InvestigationalDarusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Categories: Heterocyclic Compounds, 1-Ring, Endothelin Receptor AntagonistsXL820
go.drugbank.com/drugs/DB05146InvestigationalXL820 is a solid. … growth factor receptor alpha, clinically validated targets implicated in a variety of human cancers.
Cilnidipine
go.drugbank.com/drugs/DB09232InvestigationalCompared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium … Cilnidipine is a dihydropyridine calcium antagonist. It was jointly developed by Fuji Viscera Pharmaceutical Company, Japan and Ajinomoto, Japan and approved in 1995.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingDeferitazole
go.drugbank.com/drugs/DB13120InvestigationalIt has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red
Categories: Heterocyclic Compounds, 1-RingLobeline
go.drugbank.com/drugs/DB05137InvestigationalIt has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem]
Categories: Heterocyclic Compounds, 1-Ring