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Dalcinonacog alfa
go.drugbank.com/drugs/DB17707InvestigationalIt is being investigated for the treatment of hemophilia B.[A259058]
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
TTX-MC138
go.drugbank.com/drugs/DB18628Investigational[L48335] It is under investigation for the treatment of various metastatic cancers.
Efineptakin alfa
go.drugbank.com/drugs/DB16395InvestigationalEfineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability.
Synonyms: NT-I7R-851
go.drugbank.com/drugs/DB05747ExperimentalR-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.
QS-21
go.drugbank.com/drugs/DB05400InvestigationalIt is the leading member of the Stimulon family of adjuvants. As a vaccine additive, it is currently being evaluated in clinical trials in a variety of disease areas by Antigenics.
Enbezotinib
go.drugbank.com/drugs/DB21565InvestigationalEnbezotinib is under investigation in clinical trial NCT04161391 (Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations).