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HGS-TR2J

HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

Alglucerase

Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. … Alglucerase was first approved by the FDA in 1991;[A254816] however, it was later discontinued from the market.

Tolperisone

Based on existing clinical data, Tolperisone is not sedating and does not interact with alcohol. … It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves.

Ornithine

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine.

Zosuquidar

It is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.

Zenarestat

N-acetyl-alpha-neuraminic acid

An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)

Lefamulin

[A183206] Lefamulin is available in intravenous and oral preparations and was granted FDA approval in August 2019.

Crotalus atrox antivenin

Bites from this snake are the most common in the state of Texas, USA [A33157]. … The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F113].

Dodecyltrimethylammonium