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Paritaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationalParitaprevir first came on the market as a fixed-dose combination product with [DB09296], [DB09183], and [DB00503] as the FDA-approved product Viekira Pak. … Depending on the genotype, Paritaprevir is often used in combination with other antivirals such as [DB09296], [DB09183], [DB00503], and [DB00811], with the intent to cure, or achieve a sustained virologic
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsSynonyms: [1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrroloInodiftagene vixteplasmid
go.drugbank.com/drugs/DB16017InvestigationalInodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed … non-protein coding gene).
Synonyms: dT-A-H19, diphtheria-toxin-A-H19Monarsen
go.drugbank.com/drugs/DB16946ExperimentalSynonyms: Dna, d(c-t-g-c-g-a-t-a-t-t-t-t-c-t-t-g-t-ram-rcm-rcm)Vanglusagene ensiparvovec
go.drugbank.com/drugs/DB17675InvestigationalSynonyms: recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
go.drugbank.com/drugs/DB01765ExperimentalSynonyms: (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid, (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acidGinsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalGinsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). … Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy.
Synonyms: Panaxoside A, Ginsenoside A2Daplusiran
go.drugbank.com/drugs/DB19331InvestigationalDaplusiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis … B (CHB)).
Synonyms: RNA, (AM-SP-(2'-DEOXY-2'-FLUORO)G-SP-AM-SP-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY, -2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)C-CM-AM-SP-CM),(R)-3-hydroxydecanoyl-CoA
go.drugbank.com/drugs/DB03192ExperimentalSynonyms: (R)-3-hydroxydecanoyl-coenzyme A, (R)-3-hydroxydecanoyl-CoAOXI-4503
go.drugbank.com/drugs/DB05143InvestigationalOXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). … OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis.
Synonyms: Combretastatin A-1 bis(phosphate), Combretastatin A1 diphosphateN1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
go.drugbank.com/drugs/DB08629ExperimentalSynonyms: N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE