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Monarsen
go.drugbank.com/drugs/DB16946ExperimentalSynonyms: Dna, d(c-t-g-c-g-a-t-a-t-t-t-t-c-t-t-g-t-ram-rcm-rcm)3-thiaoctanoyl-CoA
go.drugbank.com/drugs/DB03415ExperimentalSynonyms: 3-thiaoctanoyl-coenzyme A, 3-thiaoctanoyl-CoAG100
go.drugbank.com/drugs/DB17244InvestigationalSynonyms: Glucopyranosyl Lipid A Stable Emulsion, GLA-SE(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
go.drugbank.com/drugs/DB01765ExperimentalSynonyms: (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid, (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acidVanglusagene ensiparvovec
go.drugbank.com/drugs/DB17675InvestigationalSynonyms: recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidaseExagamglogene autotemcel
go.drugbank.com/drugs/DB15572ApprovedInvestigational[L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS. … Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe
Synonyms: gene editing consisting of a guide RNA (gRNA), Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediatedDaplusiran
go.drugbank.com/drugs/DB19331InvestigationalDaplusiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis … B (CHB)).
Synonyms: RNA, (AM-SP-(2'-DEOXY-2'-FLUORO)G-SP-AM-SP-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY, -2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)C-CM-AM-SP-CM),OXI-4503
go.drugbank.com/drugs/DB05143InvestigationalOXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA).
Synonyms: Combretastatin A-1 bis(phosphate), Combretastatin A1 diphosphateN1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
go.drugbank.com/drugs/DB08629ExperimentalSynonyms: N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE