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Displaying results 4141 - 4150 of 8412 in total
  1. Drug

    Avutometinib

    go.drugbank.com/drugs/DB15254
    ApprovedInvestigational

    Avutometinib is a small molecule kinase inhibitor targeted against RAF/MEK1, key regulators of the RAS/RAF/MEK/ERK (MAPK) pathway. The MAPK pathway is implicated in variety of cancers, playing a key role in tumor cell proliferation, diff...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Deoxycholic acid

    go.drugbank.com/drugs/DB03619
    ApprovedInvestigational

    Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholi...

  3. Drug

    Golotimod

    go.drugbank.com/drugs/DB05475
    Investigational

    Due to this preferential activation of Th1 cytokine production, SCV-07 may show utility in treatment of tuberculosis. It can be administered orally or subcutaneously. … SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway.

  4. Drug

    Tocotrienol

    go.drugbank.com/drugs/DB12647
    Investigational

    Tocotrienol has been investigated for the treatment of Cholesterol Lowering.

    Mixtures: NHF Tocotrienol E Plus Vitamin D3 Softgel
  5. Drug

    Nitarsone

    go.drugbank.com/drugs/DB11437
    ExperimentalVet approved

    Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease.

    Synonyms: (p-nitrophenyl)arsonic acid, p-nitrophenylarsonic acid
  6. Drug

    Velagliflozin

    go.drugbank.com/drugs/DB20686
    Experimental

    Velagliflozin has a monoisotopic molecular weight of 395.17 Da.

  7. Drug

    Intiquinatine

    go.drugbank.com/drugs/DB20708
    Experimental

    Intiquinatine has a monoisotopic molecular weight of 387.01 Da.

  8. Drug

    Isbogrel

    go.drugbank.com/drugs/DB20766
    Experimental

    Isbogrel has a monoisotopic molecular weight of 281.14 Da.

  9. Drug

    Besigomsin

    go.drugbank.com/drugs/DB20894
    Experimental

    Besigomsin has a monoisotopic molecular weight of 416.18 Da.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  10. Drug

    Lensiprazine

    go.drugbank.com/drugs/DB20964
    Experimental

    Lensiprazine has a monoisotopic molecular weight of 422.21 Da.