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Displaying results 4141 - 4150 of 10000 in total
  1. Drug

    LY2275796

    go.drugbank.com/drugs/DB05165
    Investigational

    LY2275796 targets eukaryotic initiation factor- 4E (eIF-4E), a protein involved in the translation of key growth and survival factors that drive tumor progression, angiogenesis and metastases. … LY2275796 is a second-generation antisense anti-cancer drug candidate for clinical development.

  2. Drug

    NXN-188

    go.drugbank.com/drugs/DB06096
    Investigational

    NXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.

  3. Drug

    Sirna-027

    go.drugbank.com/drugs/DB05896
    Investigational

    It is used to treat Macular degeneration. … VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. Sirna-027 is developed by Sirna Therapeutics and is under the phase I of clinical trails.

  4. Drug

    Biricodar

    go.drugbank.com/drugs/DB04851
    Investigational

    The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).

  5. Drug

    Ametantrone

    go.drugbank.com/drugs/DB21078
    Experimental

    Ametantrone is a small molecule drug. Ametantrone has a monoisotopic molecular weight of 412.21 Da.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Elacridar

    go.drugbank.com/drugs/DB04881
    Investigational

    In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline. … Elacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors.

  7. Drug

    Dihydrolipoic Acid

    go.drugbank.com/drugs/DB03760
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Dodecyl sulfate

    go.drugbank.com/drugs/DB03967
    Investigational

    Synonyms: N-Dodecyl sulfateCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Tetradecylthioacetic acid

    go.drugbank.com/drugs/DB18802
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Patulin

    go.drugbank.com/drugs/DB15586
    Investigational

    Categories: Compounds used in a research, industrial, or household setting