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Leronlimab
go.drugbank.com/drugs/DB05941Investigational[L12684] It was first described in the literature in 2001.[A3922] This antibody binds to CCR5, which may be useful in treating HIV, cancers, and severely ill COVID-19 patients.[A192846,A192858,L12684]
IMC-1C11
go.drugbank.com/drugs/DB06101ExperimentalIt is a chimeric anti-kinase insert domain-containing receptor (KDR) antibody that blocks VEGFR-KDR interaction and inhibits VEGFR-induced endothelial cell proliferation.
Idraparinux
go.drugbank.com/drugs/DB06406InvestigationalIt was developed for the treatment and prevention of thromboembolic events. However, clinical trials have revealed that idraparinux had lead to bleeding.
Virginiamycin S1
go.drugbank.com/drugs/DB04805ExperimentalIt is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
Chloropyramine
go.drugbank.com/drugs/DB08800InvestigationalIt is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.
N-methylnicotinamide
go.drugbank.com/drugs/DB08840InvestigationalIt is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine
SynOV1.1
go.drugbank.com/drugs/DB17539InvestigationalIt is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF).
AEM-28-14
go.drugbank.com/drugs/DB17643Experimental[L45909] It is being investigated for lipid disorders such as homozygous familial hypercholesterolemia.[L45914]
ATG002
go.drugbank.com/drugs/DB05068InvestigationalATG002 is a completely new approach to treating chronic wounds such as diabetic foot ulcers, which is based upon stimulation of angiogenesis in the wound bed to help drive the wound-healing process. Unlike protein-derived growth factors,...
CMC 001
go.drugbank.com/drugs/DB05353InvestigationalCMC 001 is an orally administered MRI contrast agent in development for enhancement of the liver, bile ducts and gastrointestinal tract.