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Displaying results 4181 - 4190 of 5449 in total
  1. Drug

    Disitamab vedotin

    go.drugbank.com/drugs/DB17208
    Investigational

    It is currently being investigated for cancers.[A254721]

  2. Drug

    MGN-4893

    go.drugbank.com/drugs/DB17338
    Experimental

    In February 2011, it was granted FDA orphan designation for the treatment of polycythemia vera.[L47356]

  3. Drug

    Ixmyelocel-T

    go.drugbank.com/drugs/DB17601
    Investigational

    Ixmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.

    Synonyms: Ixmyelocel-T
  4. Drug

    Dipraglurant

    go.drugbank.com/drugs/DB12733
    Investigational

    It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).

  5. Drug

    Histrelin

    go.drugbank.com/drugs/DB06788
    ApprovedInvestigationalWithdrawn

    Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring ...

    Synonyms: [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone
  6. Drug

    CPD 923

    go.drugbank.com/drugs/DB05856
    Experimental

    It shows efficacy in vivo studies, as well as a favourable pre-clinical tolerability profile.

  7. Drug

    AP5280

    go.drugbank.com/drugs/DB05112
    Experimental

    AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.

  8. Drug

    NGX267

    go.drugbank.com/drugs/DB05152
    Investigational

    It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.

  9. Drug

    Peldesine

    go.drugbank.com/drugs/DB02568
    Investigational

    Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.

  10. Drug

    Talopram

    go.drugbank.com/drugs/DB09190
    Experimental

    It was researched in the 1960s and 1970s but never marketed.