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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Gildeuretinol

    go.drugbank.com/drugs/DB18468
    Investigational

    Synonyms: VITAMIN A ACETATE C20-D3
  2. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19. … [A265040,A265045] It works by targeting B-cell-specific CD19 surface markers present on malignant B cells.

    Synonyms: A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING O, AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODINGCategories: Genetically-modified Autologous T Cells, CD19-Directed Genetically Modified Autologous T-cell Immunotherapies
  3. Drug

    Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

    go.drugbank.com/drugs/DB01868
    Experimental

    Synonyms: Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate
  4. Drug

    N-acetyltyrosine

    go.drugbank.com/drugs/DB11102
    ApprovedInvestigational

    N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group. … It is typically administered as a source of nutritional support where oral nutrition is inadequate or cannot be tolerated.

    Mixtures: Aminoven Infant 10% w/v, AMINOPLASMAL-5% E INFUSIONSynonyms: Melanowhite-A, L-N-acetyltyrosine
  5. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe … ] - a mainstay of treatment since the 1990s - as well as newer agents like [crizanlizumab] and [voxelotor].

    Synonyms: gene editing consisting of a guide RNA (gRNA), Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated
  6. Drug

    PRGN-3006

    go.drugbank.com/drugs/DB17229
    Investigational

    PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface

    Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surface, PRGN-3006 UltraCAR-T
  7. Drug

    Bambermycins

    go.drugbank.com/drugs/DB11377
    ExperimentalVet approved

    They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.

    Synonyms: Moenomycin A
  8. Drug

    N-Ethylretinamide

    go.drugbank.com/drugs/DB03917
    Experimental

    N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.

    Synonyms: Vitamin A acid ethylamide, all-trans-N-EthylretinamideCategories: Vitamin A
  9. Drug

    3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside

    go.drugbank.com/drugs/DB02346
    Experimental

    Synonyms: 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside
  10. Drug

    1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene

    go.drugbank.com/drugs/DB03634
    Experimental

    Synonyms: 1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene