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Displaying results 4191 - 4200 of 10000 in total
  1. Drug

    Fluperolone

    go.drugbank.com/drugs/DB13491
    Experimental

    Categories: Corticosteroids, Moderately Potent (Group II)
  2. Drug

    N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate

    go.drugbank.com/drugs/DB02643
    Experimental

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate
  3. Drug

    Seletracetam

    go.drugbank.com/drugs/DB05885
    Investigational

    It is predicted to have low drug-drug interactions and inhibition or induction of any major human metabolizing enzymes. Seletracetam was in Phase II clinical trials under the supervision of the U.S. … Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam.

  4. Drug

    Pegvisomant

    go.drugbank.com/drugs/DB00082
    ApprovedInvestigational

    Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. … Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main

  5. Drug

    Thiacloprid

    go.drugbank.com/drugs/DB08620
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    MDX-1379

    go.drugbank.com/drugs/DB05329
    Investigational

    This drug is underinvestigation to treat malignant melanoma.

  7. Drug

    Sulfinpyrazone

    go.drugbank.com/drugs/DB01138
    Approved

    A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

  8. Drug

    Glycochenodeoxycholic Acid

    go.drugbank.com/drugs/DB02123
    Experimental

    A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. … It is a cholagogue and choleretic. [PubChem]

    Categories: Compounds used in a research, industrial, or household setting, N-substituted Glycines
  9. Drug

    SN-38

    go.drugbank.com/drugs/DB05482
    Investigational

    7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer … SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others.

    Categories: Topoisomerase I Inhibitors
  10. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation.