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INCB7839
go.drugbank.com/drugs/DB05033InvestigationalIt represents a potentially important new class of targeted breast cancer therapy. It has shown promising clinical activity in heavily pretreated, refractory breast cancer patients. … INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways.
Imazaquin
go.drugbank.com/drugs/DB04582ExperimentalCategories: Compounds used in a research, industrial, or household setting2,5-di-tert-butylhydroquinone
go.drugbank.com/drugs/DB04638ExperimentalCategories: Compounds used in a research, industrial, or household settingAmibegron
go.drugbank.com/drugs/DB05395InvestigationalAmibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
AT9283
go.drugbank.com/drugs/DB05169InvestigationalAT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Deramciclane
go.drugbank.com/drugs/DB06512InvestigationalDeramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target. … Deramciclane (EGIS-3886) is used for the treatment of a number of anxiety disorders.
MKC1106-PP
go.drugbank.com/drugs/DB06030ExperimentalMKC1106-PP was under investigation in clinical trial NCT00423254 (Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.). … MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM.
Potassium triiodide
go.drugbank.com/drugs/DB14492InvestigationalCategories: Compounds used in a research, industrial, or household settingSirna-027
go.drugbank.com/drugs/DB05896InvestigationalVEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. Sirna-027 is developed by Sirna Therapeutics and is under the phase I of clinical trails. … Sirna-027 is a chemically modified short interfering RNA(siRNA) targeting Vascular Endothelial Growth Factor Receptor-1(VEGFR-1).