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Inecalcitol

AZD-8330

AZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.

Nirogacestat

Desmoid tumors are typically characterized by aberrant activation in Notch signaling. … It was previously granted breakthrough therapy, fast track, and orphan drug designations for the treatment of desmoid tumors, and the final approval was based on positive results obtained in the Phase

Citrulline

Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. … It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.

Epratuzumab

This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. … Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2).

YSIL6

YSIL6 is a small-molecule drug in development for the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. … The molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration.

Vesnarinone

Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.

Vapreotide

Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.

Aluminium

A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

Dipicolinic acid