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QS-21
go.drugbank.com/drugs/DB05400InvestigationalIt is the leading member of the Stimulon family of adjuvants. As a vaccine additive, it is currently being evaluated in clinical trials in a variety of disease areas by Antigenics.
Diacetyl benzoyl lathyrol
go.drugbank.com/drugs/DB11260ApprovedIt is also reported to be a skin conditioning agent.
Ohmefentanyl
go.drugbank.com/drugs/DB01570ExperimentalIllicitOhmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently named F9201–F9208. … Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which are used for tranquilizing large animals such as elephants
Olmutinib
go.drugbank.com/drugs/DB13164InvestigationalIt is available under the brand name Olita made by Hanmi Pharmaceuticals [A19196]. Olmutinib was developed by Hanmi Pharmaceuticals and Boehringer Ingelheim. … Olmutinib recieved breakthrough therapy designation in the United States in December 2015 and was approved for use in Korea in May 2016.
Drozitumab
go.drugbank.com/drugs/DB19106InvestigationalIt was developed by Genentech as a drug for the treatment of cancers
SB-269970
go.drugbank.com/drugs/DB13988ExperimentalIn the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]
Apramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedIt is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.
Bradanicline
go.drugbank.com/drugs/DB06090InvestigationalBradanicline, a novel small molecule that modulates the activity of the neuronal nicotinic receptor (NNR) subtype known as alpha7(α7).
Lortalamine
go.drugbank.com/drugs/DB09187ExperimentalThis drug never made it past clinical trials, likely due to ocular toxicity in animals, but has been used in positron emission tomography studies to label norepinephrine transporters.
Betameprodine
go.drugbank.com/drugs/DB01552ExperimentalIllicitIt exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, as well as itching, nausea, and respiratory depression. … The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine.