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MF-300
go.drugbank.com/drugs/DB32060InvestigationalAs a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983] … MF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase.
AAV8-RK-RetGC
go.drugbank.com/drugs/DB32389ExperimentalAAV8-RK-RetGC is an adeno-associated virus (AAV) viral vector platform with a serotype 8 capsid with a complementary DNA (cDNA) of the human GUCY2D gene encoding RetGC.
GLB-004
go.drugbank.com/drugs/DB32796ExperimentalGLB-004 is a molecular glue degrader targeting ARNT(HIF-1β).[L56125, L56126]
GLB-005
go.drugbank.com/drugs/DB32797ExperimentalGLB-005 is a molecular glue degrader targeting WIZ and is being investigated for treatment of sickle cell disease and β-thalassemia.[L56125, L56126, L56128]
GLB-007
go.drugbank.com/drugs/DB32798ExperimentalGLB-007 is a molecular glue degrader targeting WIZ and ZBTB7A.[L56125, L56126, L56128]
GLB-006
go.drugbank.com/drugs/DB32799ExperimentalGLB-006 is a molecular glue degrader targeting NEK7.[L56125, L56126]
CD68-ET3-LV
go.drugbank.com/drugs/DB32864InvestigationalCD68-ET3-LV is an autologous gene therapy consisting of CD34+ hematopoietic stem and progenitor cells transduced ex-vivo with the CD68-ET3-LV lentiviral vector.
APT20TTMG
go.drugbank.com/drugs/DB32869ExperimentalAPT20TTMG is a synthetic DNA that modulates U1 small nuclear ribonucleoprotein misassembly.