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Bencyclane
go.drugbank.com/drugs/DB13488ExperimentalIt has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt was determined that polaprezinc may be effective in pressure ulcer treatment [A31856]. … It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308].
XP12B
go.drugbank.com/drugs/DB04928InvestigationalIt was granted Fast Track status for this indication by the FDA in November 2004.
ALMB-0166
go.drugbank.com/drugs/DB17937InvestigationalIt was granted FDA orphan designation in November 2018.[L47067]
AGuIX
go.drugbank.com/drugs/DB18189InvestigationalIt is under development as a radiosensitizer to be used during radiation treatment of malignant glioma.
Oremepermin alfa
go.drugbank.com/drugs/DB27148Investigational[L54006] It is produced in CHO cells.[L54006]
WX-UK1
go.drugbank.com/drugs/DB05476InvestigationalWX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of drugs. In animal models, WX-UK1 blocks tumor cell invasion, metastasis and primary tumor growth by inhibiting serine proteases and the u...
Carbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationalIt is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought … In New Zealand, the use of carbon monoxide in fish preparation has been banned, as it may mask the effects of food spoilage and bacterial growth [L2539].
Zidesamtinib
go.drugbank.com/drugs/DB21623ApprovedInvestigational[L63808,L63933] Zidesamtinib is selective for ROS1, retains activity in cells carrying the common resistance mutations, and showed antitumor activity in an intracranial model, positioning it for use after