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Displaying results 431 - 440 of 10000 in total
  1. Drug

    Monensin

    go.drugbank.com/drugs/DB11430
    ExperimentalVet approved

    Monensin is a polyether isolated from _Streptomyces cinnamonensis_ that presents antibiotic properties. It is widely used in ruminant animal feeds.

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: Monensin A
  2. Drug

    CER-001

    go.drugbank.com/drugs/DB18538
    Investigational

    CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. … [L48290] It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.

    Categories: Apolipoproteins ASynonyms: Recombinant human apolipoprotein A-I/phospholipid complexes
  3. Drug

    3-thiaoctanoyl-CoA

    go.drugbank.com/drugs/DB03415
    Experimental

    Synonyms: 3-thiaoctanoyl-coenzyme A, 3-thiaoctanoyl-CoA
  4. Drug

    Paritaprevir

    go.drugbank.com/drugs/DB09297
    ApprovedInvestigational

    In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Paritaprevir as a first line … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: [1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo
  5. Drug

    TN-201

    go.drugbank.com/drugs/DB18700
    Investigational

    TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.

    Synonyms: Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene
  6. Drug

    (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid

    go.drugbank.com/drugs/DB01765
    Experimental

    Synonyms: (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid, (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acid
  7. Drug

    Prexigebersen

    go.drugbank.com/drugs/DB17320
    Investigational

    Synonyms: Dna, d(a-t-a-t-t-t-g-g-c-g-a-t-g-g-c-t-t-c), L-grb-2 antisense
  8. Drug

    Inodiftagene vixteplasmid

    go.drugbank.com/drugs/DB16017
    Investigational

    Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed

    Synonyms: dT-A-H19, diphtheria-toxin-A-H19
  9. Drug

    Monarsen

    go.drugbank.com/drugs/DB16946
    Experimental

    Synonyms: Dna, d(c-t-g-c-g-a-t-a-t-t-t-t-c-t-t-g-t-ram-rcm-rcm)
  10. Drug

    Vanglusagene ensiparvovec

    go.drugbank.com/drugs/DB17675
    Investigational

    Synonyms: recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase