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Teprasiran
go.drugbank.com/drugs/DB15064InvestigationalTeprasiran is under investigation in clinical trial NCT03510897 (QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery).
Adebrelimab
go.drugbank.com/drugs/DB16412InvestigationalAdebrelimab is under investigation in clinical trial NCT03711305 (Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-stage (ES) Small Cell Lung Cancer
AUTO3
go.drugbank.com/drugs/DB17364InvestigationalIt is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22. … AUTO3 is bicistronic chimeric antigen receptor T-cell therapy investigated for acute lymphoblastic leukemia (ALL).
KITE-585
go.drugbank.com/drugs/DB17409InvestigationalKITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
NP-6A4
go.drugbank.com/drugs/DB17599ExperimentalIt has an Orphan Drug designation from the FDA for pediatric cardiomyopathy.[A258523]
Eftansomatropin alfa
go.drugbank.com/drugs/DB18460Investigational[L48275] It is under investigation for the treatment of growth hormone deficiency.
Vezocolmitide
go.drugbank.com/drugs/DB21751InvestigationalVezocolmitide is under investigation in clinical trial NCT06178679 (Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease
Synonyms: ST-1009,10-Deepithio-9,10-Didehydroacanthifolicin
go.drugbank.com/drugs/DB02169ExperimentalIt is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
Brasofensine
go.drugbank.com/drugs/DB04857ExperimentalBrasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K. In November 2001, NeuroSearch confirmed that ...
Cedazuridine
go.drugbank.com/drugs/DB15694ApprovedInvestigationalMyelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated. Hypomethylating agents such as d...