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Androstenediol
go.drugbank.com/drugs/DB01524ExperimentalIllicitAndrostenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group … Androstenediol is an intermediate in [testosterone] biosynthesis, found in the testis or the adrenal glands.
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedIts insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis … All the abovementioned effects are translated into the overexcitation, paralysis, and death in insects.
L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal
go.drugbank.com/drugs/DB06124ExperimentalC-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal … Calpain is the primary protease that degrades skeletal muscle.
Human papillomavirus type 52 L1 capsid protein antigen
go.drugbank.com/drugs/DB10313ApprovedInvestigationalIt is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like particles … (VLPs) of the major capsid (L1) protein of HPV Type 52 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled into VLPs.
Gaxilose
go.drugbank.com/drugs/DB12767ApprovedWithdrawnGaxilose has been used in trials studying the diagnostic of Lactose Intolerance.
CE-224535
go.drugbank.com/drugs/DB12113InvestigationalCE-224535 has been used in trials studying the treatment of Osteoarthritis.
Pentetreotide
go.drugbank.com/drugs/DB12602ApprovedWithdrawnPentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.
CE-326597
go.drugbank.com/drugs/DB12694InvestigationalCE-326,597 has been used in trials studying the treatment of Obesity.
Parethoxycaine
go.drugbank.com/drugs/DB19380ApprovedWithdrawnParethoxycaine is a local anesthetic that was previously approved in the US.
Merimepodib
go.drugbank.com/drugs/DB04862InvestigationalMerimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.