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Displaying results 4481 - 4490 of 7063 in total
  1. Drug

    Nerofe

    go.drugbank.com/drugs/DB14786
    Investigational

    Nerofe is under investigation in clinical trial NCT03059615 (A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS).

    Synonyms: WWTFFLPSTLWERK, (ALL D)-, TRP-TRP-THR-PHE-PHE-LEU-PRO-SER-THR-LEU-TRP-GLU-ARG-LYS, (ALL D)-
  2. Drug

    Dapansutrile

    go.drugbank.com/drugs/DB16130
    Investigational

    Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).

  3. Drug

    Abt-925 anhydrous free base

    go.drugbank.com/drugs/DB33803
    Investigational

    Categories: Receptors, Dopamine D3, antagonists & inhibitors
  4. Drug

    Sabirnetug

    go.drugbank.com/drugs/DB19438
    Investigational

    Sabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).

  5. Drug

    Psilocybin

    go.drugbank.com/drugs/DB11664
    Investigational

    In November, 2019, it was granted Breakthrough Therapy status by the FDA.

  6. Drug

    INVAC-1

    go.drugbank.com/drugs/DB16196
    Investigational

    INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

    Synonyms: Human telomerase reverse transcriptase (htert) dna vaccine invac-1, Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse transcriptase (htert) fusion protein
  7. Drug

    ZYCOV-D

    go.drugbank.com/drugs/DB15892
    Experimental

    The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest[L16503]. … The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758].

  8. Drug

    αAβ–Gas6

    go.drugbank.com/drugs/DB17069
    Experimental

    of AD. … It is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand

  9. Drug

    Blonanserin

    go.drugbank.com/drugs/DB09223
    Investigational

    As a second-generation (atypical) antipsychotic, it is significantly more efficacious in the treatment of the negative symptoms of schizophrenia compared to first-generation (typical) antipsychotics.

    Categories: Dopamine D2 Receptor Antagonists
  10. Drug

    Tisotumab vedotin

    go.drugbank.com/drugs/DB16732
    ApprovedInvestigational

    agent, via a protease-cleavable valine-citrulline linker. … On April 29, 2024, tisotumab vedotin was granted full FDA approval.