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Displaying results 441 - 450 of 10000 in total
  1. Drug

    2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide

    go.drugbank.com/drugs/DB08046
    Experimental

    Synonyms: 2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide
  2. Drug

    5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB08234
    Experimental

    Synonyms: 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
  3. Drug

    Linagliptin

    go.drugbank.com/drugs/DB08882
    ApprovedInvestigational

    Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050 … Linagliptin was approved by the FDA on May 2, 2011[L9557].

    Mixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MGCategories: Drugs Used in Diabetes, P-glycoprotein inhibitors
  4. Drug

    Osimertinib

    go.drugbank.com/drugs/DB09330
    ApprovedInvestigational

    Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs due to the presence of specific activating EGFR mutations within the tumour cells. … testing and which has progressed following therapy with a first-generation EGFR tyrosine kinase inhibitor.

    Synonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index
  5. Drug

    IDM-1

    go.drugbank.com/drugs/DB05292
    Experimental

    It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc. … IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer.

    Synonyms: IDM-1
  6. Drug

    1-deoxymannojirimycin

    go.drugbank.com/drugs/DB03955
    Experimental

    An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: D-manno-Deoxynojirimycin, 1-deoxymannojirimycin
  7. Drug

    5-Bromoindirubin

    go.drugbank.com/drugs/DB07493
    Experimental

    Synonyms: (2Z)-5'-bromo-2,3'-biindole-2',3(1H,1'H)-dione ammoniate, 5-Bromoindirubin
  8. Drug

    1-Methylcytosine

    go.drugbank.com/drugs/DB04314
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Methylcytosine, N-Methylcytosine
  9. Drug

    INVAC-1

    go.drugbank.com/drugs/DB16196
    Investigational

    INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

    Synonyms: Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse transcriptase (htert) fusion protein, Human telomerase reverse transcriptase (htert) dna vaccine invac-1
  10. Drug

    5-fluorouridine

    go.drugbank.com/drugs/DB01629
    Investigational

    5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. … These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-Fluorouracil 1beta-D-ribofuranoside, 5-Fur