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Pantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigational[A177577, A177580] Pantoprazole doses should be slowly lowered, or tapered, before discontinuing as rapid discontinuation of PPIs such as pantoprazole may cause a rebound effect and a short term increase … [FDA Label] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Mixtures: OCAM® DUO.Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: CİBADREX 5/6,25 MG FİLM TABLET, 28 ADET, CİBADREX 10/12,5 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: RIVAROXABAN EG, RIVAROXABAN EG STADAZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525] … generally thought to be as efficacious as first generation antipsychotics but differ in their adverse effect profiles.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsProducts: ZELDOX IM ENJ. SOL. ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET, GEODON® CAPSULAS 80 MGKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine].
Categories: Heterocyclic Compounds, 1-RingProducts: KETOTIFENE EG, KETEN SYRUP 1 mg/5 mlNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigationalNebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. … [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are first treated with thiazide diuretics.
Mixtures: AMLONEB 5 MG/5 MG TABLET, 30 ADET, AMLONEB 5 MG/5 MG TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AgonistsEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.[L12975] … Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].
Synonyms: L-erythro-2-(Methylamino)-1-phenylpropan-1-ol, (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropaneMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, COPHADYL-E COUGH LINCTUSCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: Calcipotriene 0.005% / Niacinamide 4%, DAIVOBET® GEL 50 MCG + 0.5 MG/ GCategories: Vitamin D and AnaloguesAngelica archangelica root
go.drugbank.com/drugs/DB14283ApprovedAngelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: Park no suk a clear walk of parkMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Synonyms: (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamide, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamideCategories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor Agonists