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Human Umbilical Cord Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15726InvestigationalThe cells are extracted by either the explant or the enzymatic digestion method, though neither method has been characterized as the ‘standard’ thus far. … Currently many companies are creating their own version of these stem cells, one of which is by Aspire, who are creating a version named ACT-20.
Cyclic nucleotide phosphodiesterase
go.drugbank.com/bio_entities/BE0004922TargetHumansHydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes
Synonyms: Cell proliferation-inducing gene 22 proteinNADPH oxidase
go.drugbank.com/bio_entities/BE0004904TargetHumansRequired for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its … In neurons, plays a crucial role in regulating GABA(A) receptor synaptic stability and hence GABAergic inhibitory synaptic transmission through its role in PAK1 activation and eventually F-actin stabilization
Synonyms: Cell migration-inducing gene 5 proteinTetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalThese effects are largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 (CB1 and CB2)[A32585]. … Beyond the endocannabinoid system, THCV has also been reported to activate 5HT1A receptors to produce an antipsychotic effect that has therapeutic potential for ameliorating some of the negative, cognitive
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin Receptor AgonistsVoltage-gated Potassium Channels
go.drugbank.com/bio_entities/BE0009847TargetSuppressed by activation of the muscarinic acetylcholine receptor CHRM1 (PubMed:10684873, PubMed:10713961) … Similar to the native M-channel, KCNQ3-KCNQ5 potassium channel is suppressed by activation of the muscarinic acetylcholine receptor CHRM1 (PubMed:10816588)
Synonyms: AMME syndrome candidate gene 2 protein, Ether-a-go-go-related gene potassium channel 1Cyclin-dependent kinases
go.drugbank.com/bio_entities/BE0010231TargetHumansEZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing (PubMed:20935635). … EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing (PubMed:20935635).
Synonyms: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 proteinFunction: acetylcholine receptor activator activityColesevelam
go.drugbank.com/drugs/DB00930ApprovedInvestigationalColesevelam is a bile acid sequestrant.
Ethiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedProducts: LIPIODOL ® ULTRA-FLUIDE, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 MLNadolol
go.drugbank.com/drugs/DB01203ApprovedInvestigationalNadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure. … [L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and
Mixtures: Corzide Tab W Nadolol 80mg, Corzide Tab W Nadolol 40mgCategories: MATE 1 Substrates, MATE 2 SubstratesStreptococcus pneumoniae type 3 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10321ApprovedInvestigationalStreptococcus pneumoniae type 3 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 3 of *Streptococcus pneumoniae*.
Synonyms: pneumococcal capsular polysaccharide type 3 vaccine, Streptococcus pneumoniae type 3 capsular polysaccharide antigenMixtures: PNEUMOVAX ® 23 (VACUNA PNEUMOCOCO POLIVALENTE), PNEUMOVAX 23 0,5 ML ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET