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LC16M8

LC16m8 is a next-generation, attenuated smallpox vaccine that is designed to have a better safety profile, yet be equally effective, compared to conventional smallpox vaccines. … It is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.

Vapreotide

Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.

Trastuzumab emtansine

Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic … Second that there is a black box warning of serious side effects such as hepatotoxicity, embryo-fetal toxicity, and cardiac toxicity.

Nafamostat

The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing continuous renal replacement therapy due to acute kidney injury. … Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties.

TG-100801

It is administered noninvasively as an eye drop and is designed to suppress VEGF mediated leakage and additional kinase targets associated with inflammation, edema, and angiogenesis which are the pathological … TG100801 is a topically applied kinase inhibitor in macular degeneration patients.

Ioxilan

Ioxilan is a tri-iodinated diagnostic contrast agent.

TRC093

TRC093 is a recombinant humanized IgG1k monoclonal antibody.

Benzimate

Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. … It is currently under investigation by AmpliMed and is in phase I of clinical trial.

Metrizamide

It is also used as a resorbable, non-ionic contrast medium. … Metrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity.

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