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Displaying results 4581 - 4590 of 10000 in total
  1. Drug

    Nadofaragene firadenovec

    go.drugbank.com/drugs/DB17381
    ApprovedInvestigational

    [A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and promotes the transduction of IFNα2b. … [L44381] It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma _in situ_ (CIS)

    Categories: Complex Mixtures
  2. Drug

    Hydroxytyrosol

    go.drugbank.com/drugs/DB12771
    Investigational

    Hydroxytyrosol has been used in trials studying the prevention of Breast Cancer.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Cusatuzumab

    go.drugbank.com/drugs/DB15100
    Investigational

    CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival. … An overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety of solid and hematological malignancies.

  4. Drug

    Pracinostat

    go.drugbank.com/drugs/DB05223
    Investigational

    Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing. … Data demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors.

  5. Drug

    Vespula maculifrons venom protein

    go.drugbank.com/drugs/DB10956
    Approved

    Vespula maculifrons venom protein is an extract of Vespula maculifrons venom. Vespula maculifrons venom protein is used in allergenic testing.

  6. Drug

    Polistes annularis venom protein

    go.drugbank.com/drugs/DB11027
    Approved

    Polistes annularis venom protein is an extract of Polistes annularis venom. Polistes annularis venom protein is used in allergenic testing.

  7. Drug

    Vespula germanica venom protein

    go.drugbank.com/drugs/DB11030
    Approved

    Vespula germanica venom protein is an extract of Vespula germanica venom. Vespula germanica venom protein is used in allergenic testing.

  8. Drug

    Elm

    go.drugbank.com/drugs/DB14258
    Approved

    Elm is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: GLP Core
  9. Drug

    Wormwood

    go.drugbank.com/drugs/DB14291
    Approved

    Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  10. Drug

    Otelixizumab

    go.drugbank.com/drugs/DB05496
    Investigational

    Otelixizumab is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. … Otelixizumab is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance