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Displaying results 4581 - 4590 of 8010 in total
  1. Drug

    Cimetropium

    go.drugbank.com/drugs/DB09271
    Investigational

    It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada.

    Categories: Drugs for Functional Gastrointestinal Disorders
  2. Drug

    BOS172722

    go.drugbank.com/drugs/DB15498
    Investigational

    The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. … [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.[A187123]

  3. Drug

    Farnesol

    go.drugbank.com/drugs/DB02509
    Investigational

    (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) … A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose.

  4. Drug

    Tilarginine

    go.drugbank.com/drugs/DB11815
    ApprovedInvestigationalWithdrawn

    Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.

  5. Drug

    Demecarium

    go.drugbank.com/drugs/DB00944
    Approved

    It is a cholinesterase inhibitor or an anticholinesterase. … Cholinesterase inhibitors prolong the effect of acetylcholine, which is released at the neuroeffector junction of parasympathetic postganglion nerves, by inactivating the cholinesterases that break it

  6. Drug

    Quinupristin

    go.drugbank.com/drugs/DB01369
    Approved

    Quinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium.

  7. Drug

    Vapreotide

    go.drugbank.com/drugs/DB04894
    Investigational

    It was being studied for the treatment of cancer.

  8. Drug

    1D09C3

    go.drugbank.com/drugs/DB05121
    Experimental

    The antibody was isolated in collaboration with MorphoSys from its HuCAL(R) library of human antibodies. 1D09C3 binds to certain cell surface receptors, selectively killing activated, proliferating MHC … class II-positive tumor cells, which include those in B-cell and T-cell lymphomas. 1D09C3 has been shown to induce programmed cell death and does not require a functioning immune system for its cell-killing

  9. Drug

    Pradefovir mesylate

    go.drugbank.com/drugs/DB05478
    Investigational

    Pradefovir is undergoing phase II development for the treatment of chronic hepatitis B. … Pradefovir is activated through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver.

  10. Drug

    Dihydroergocristine

    go.drugbank.com/drugs/DB13345
    Approved

    [L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline.

    Categories: Heterocyclic Compounds with 4 or More Rings