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Calcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … There is also evidence that calcitriol modulates the action of cytokines and may regulate immune and inflammatory response, cell turnover, cell differentiation [A26353].
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3Coagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100Approvedmedium that is then processed and purified for use as a pharmaceutical agent. … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.
Products: IMMUNINE ® 600 U.I. CONCENTRADO DE FACTOR IX, OCTANINE® F 500 UICiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
Synonyms: citidin difosfato de colina, Cytidine 5'-diphosphocholineCategories: Heterocyclic Compounds, 1-RingIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.
Synonyms: 2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-oneMixtures: Van-irbesartan-hctz, Van-irbesartan-hctzFB-825
go.drugbank.com/drugs/DB17598InvestigationalFB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Synonyms: Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment of human membrane-bound immunoglobulin E (mIgE)Tranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.
Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidInternational brands: Cyclo-FLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. … [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Van-letrozole, Mar-letrozoleIlex paraguariensis leaf
go.drugbank.com/drugs/DB14366InvestigationalIlex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Mat, Yerba MatDexrabeprazole
go.drugbank.com/drugs/DB13762InvestigationalCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: Rabeprazole, (r)-Verapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalgreater potency than the R-enantiomer, but is metabolized at a higher rate. … [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold
Mixtures: Trandolapril and Verapamil Hydrochloride ER, Trandolapril and Verapamil Hydrochloride ERCategories: MATE 1 Inhibitors, MATE 2 Inhibitors