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Doxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigationalDoxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:...
CTx-PDE6b
go.drugbank.com/drugs/DB17858InvestigationalBeing commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to _PDE6b_ gene mutations.[L46757]
Vemtoberant
go.drugbank.com/drugs/DB21607InvestigationalVemtoberant has a monoisotopic molecular weight of 619.2 Da.
Delocamten
go.drugbank.com/drugs/DB21711InvestigationalDelocamten has a monoisotopic molecular weight of 377.16 Da.
H3B-8800
go.drugbank.com/drugs/DB14017InvestigationalH3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no...
Tasurgratinib
go.drugbank.com/drugs/DB21222InvestigationalTasurgratinib has a monoisotopic molecular weight of 587.27 Da.
AdimrSC-2f
go.drugbank.com/drugs/DB16436InvestigationalThe AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553].
Eplontersen
go.drugbank.com/drugs/DB16199ApprovedInvestigationalanalysis from the Phase 3 NEURO-TTRansform study, where a consistent improvement in the Neuropathy Impairment Score +7 (mNIS+7) and the Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (Norfolk QoL-DN
Cyamemazine
go.drugbank.com/drugs/DB09000ExperimentalCyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).