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Displaying results 4641 - 4650 of 9670 in total
  1. Drug

    DDP-225

    go.drugbank.com/drugs/DB05642
    Investigational

    DDP225 is both a noradrenaline reuptake inhibitor and a serotonin type 3 receptor (5-HT3) antagonist. Noradrenaline and serotonin are neurotransmitters that are known to be involved in the control of the gastrointestinal system. The uniq...

  2. Drug

    Eptotermin alfa

    go.drugbank.com/drugs/DB11631
    ApprovedWithdrawn

    It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.

  3. Drug

    Clopamide

    go.drugbank.com/drugs/DB13792
    Investigational

    Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.

  4. Drug

    AUM-601

    go.drugbank.com/drugs/DB17382
    Experimental

    AUM-601 is a highly selective pan-TRK(tropomyosin receptor kinase). It is currently being investigated in clinical trials for the treatment of cancer.

  5. Drug

    Zirconium panitumumab Zr-89

    go.drugbank.com/drugs/DB19228
    Investigational

    Zirconium panitumumab Zr-89 is under investigation in clinical trial NCT05423197 (Study Evaluating Zr-panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous

  6. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.

  7. Drug

    Andrographolide

    go.drugbank.com/drugs/DB05767
    Investigational

    The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.

  8. Drug

    MGN-4893

    go.drugbank.com/drugs/DB17338
    Experimental

    In February 2011, it was granted FDA orphan designation for the treatment of polycythemia vera.[L47356]

  9. Drug

    Dipraglurant

    go.drugbank.com/drugs/DB12733
    Investigational

    Dipraglurant has been used in trials studying the treatment of Parkinson's Disease. It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).

  10. Drug

    MPT0B640

    go.drugbank.com/drugs/DB16512
    Investigational

    MPT0B640 was under investigation in clinical trials NCT04526717 for COVID-19 infection and NCT04294875 for locally advanced or metastatic solid malignancies.