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Displaying results 4671 - 4680 of 10000 in total
  1. Drug

    ICA-105665

    go.drugbank.com/drugs/DB06089
    Investigational

    In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain. … It is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy.

  2. Drug

    Proscillaridin

    go.drugbank.com/drugs/DB13307
    Experimental

    Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). … Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Nitrilotriacetic acid

    go.drugbank.com/drugs/DB03040
    Experimental

    Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Theralizumab

    go.drugbank.com/drugs/DB15717
    Investigational

    After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]

  5. Drug

    Eliapixant

    go.drugbank.com/drugs/DB21465
    Investigational

    Eliapixant has a monoisotopic molecular weight of 478.13 Da. … Eliapixant is under investigation in clinical trial NCT04614246 (Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive

  6. Drug

    Itrocainide

    go.drugbank.com/drugs/DB20210
    Experimental

    Itrocainide has a monoisotopic molecular weight of 361.22 Da. … The usage of the INN stem '-cain-' in the name indicates that Itrocainide is a class I antiarrhythmic, procainamide and lidocaine derivative.

  7. Drug

    Asoprisnil ecamate

    go.drugbank.com/drugs/DB20225
    Experimental

    The usage of the INN stem '-nil' in the name indicates that Asoprisnil ecamate is a benzodiazepine receptor antagonist/agonist. Asoprisnil ecamate has a monoisotopic molecular weight of 520.29 Da.

  8. Drug

    Ripisartan

    go.drugbank.com/drugs/DB20229
    Experimental

    Ripisartan has a monoisotopic molecular weight of 426.19 Da. … The usage of the INN stem '-sartan' in the name indicates that Ripisartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic).

  9. Drug

    Ditiomustine

    go.drugbank.com/drugs/DB20264
    Experimental

    Ditiomustine has a monoisotopic molecular weight of 420.02 Da. … The usage of the INN stem '-mustine' in the name indicates that Ditiomustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative.

  10. Drug

    Alestramustine

    go.drugbank.com/drugs/DB20270
    Experimental

    Alestramustine has a monoisotopic molecular weight of 510.21 Da. … The usage of the INN stem '-mustine' in the name indicates that Alestramustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative.