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Minaprine
go.drugbank.com/drugs/DB00805ApprovedMinaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant re...
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Serotonin Receptor AntagonistsDenufosol
go.drugbank.com/drugs/DB04983InvestigationalDenufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial. … A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in lung function for cystic fibrosis patients taking denufosol.
Clometocillin
go.drugbank.com/drugs/DB13686ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRipasudil
go.drugbank.com/drugs/DB13165InvestigationalIt was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the brand name Glanatec. … Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension.
Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran. Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom ...
ARCoV
go.drugbank.com/drugs/DB15855ExperimentalAs of July 2020, the vaccine candidate is set for Phase 1 clinical trials to investigate for safety, tolerance, and immunogenicity (ChiCTR2000034112). … Manufactured as a liquid, ARCoV is thermostable at room temperature for at least 1 week.
Vibriolysin
go.drugbank.com/drugs/DB05135ExperimentalIt is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds.
Detomidine
go.drugbank.com/drugs/DB11556InvestigationalVet approvedCurrently, it is only approved by the FDA for use in horses but has been studied for use in other large animals.
Categories: Adrenergic alpha-2 Receptor AgonistsEfprezimod alfa
go.drugbank.com/drugs/DB16448InvestigationalCD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Categories: Experimental Unapproved Treatments for COVID-19Sarconeos
go.drugbank.com/drugs/DB16457InvestigationalSarconeos is an activator of the MAS receptor.
Categories: Experimental Unapproved Treatments for COVID-19