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AZD-2836
go.drugbank.com/drugs/DB06031Investigational[A264853] The drug is being investigated for treatment of hepatitis C because AZD-2836 has in vitro anti-HCV activity.[A264858]
Synonyms: 6-(3,4-Dimethoxyphenyl)-N-[4-(1H-1,2,4-triazol-1-yl)phenyl]-4-quinazolinamineLazertinib
go.drugbank.com/drugs/DB16216ApprovedInvestigational[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184] … [A264299, A264304] Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of _EGFR_ T790M mutation-positive non-small cell lung cancer (NSCLC) with EGFR mutations.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDEFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Mixtures: FULDUO 100 MG/8 MG FİLM KAPLI TABLET, 14 ADET, MULTIFLEX 200/8 MG SR KAPSUL, 14 ADETCategories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSLidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedIn particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety … Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis.
Synonyms: 2-(Diethylamino)-2',6'-acetoxylidide, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideInternational brands: L-Caine, Lidoject-1Thiabendazole
go.drugbank.com/drugs/DB00730ApprovedVet approvedWithdrawn2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-(thiazol-4-yl)benzimidazole, 4-(2-benzimidazolyl)thiazoleNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, TILIDIN 50/4 RETARD 1A PHACategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine
go.drugbank.com/drugs/DB01988ExperimentalSynonyms: 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)PyrazineN-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide
go.drugbank.com/drugs/DB08351ExperimentalSynonyms: N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE
go.drugbank.com/drugs/DB08495ExperimentalSynonyms: 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDEN-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE
go.drugbank.com/drugs/DB07272ExperimentalSynonyms: N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE