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Displaying results 4911 - 4920 of 10000 in total
  1. Drug

    Atipamezole

    go.drugbank.com/drugs/DB11481
    InvestigationalVet approved

    It has also been undergone research as a potential anti-Parkinsonian drug for humans. … Atipamezole is a synthetic α2 adrenoceptor antagonistused to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.

  2. Drug

    Exbivirumab

    go.drugbank.com/drugs/DB17747
    Experimental

    It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202] … Exbivirumab is an investigational monoclonal antibody.

  3. Drug

    Dibekacin

    go.drugbank.com/drugs/DB13270
    Approved

    Dibekacin is an aminoglycoside antibiotic marketed in Japan [L5623].

  4. Drug

    BO-653

    go.drugbank.com/drugs/DB19216
    Investigational

    BO-653 is under investigation in clinical trial NCT00055510 (A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and … Effectiveness in Preventing Post-angioplasty Blood Vessel Re-closure (Restenosis) in Stented Vessels.).

  5. Drug

    PI-166

    go.drugbank.com/drugs/DB05859
    Experimental

    It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.

  6. Drug

    Talampanel

    go.drugbank.com/drugs/DB04982
    Investigational

    Talampanel is a substance that is being studied in the treatment of brain tumors and other brain disorders, such as epilepsy and Parkinson disease. It is a type of AMPA receptor antagonist.

  7. Drug

    Linseed oil

    go.drugbank.com/drugs/DB11357
    Investigational

    It is used in drying processes, and is used in other industrial and commercial applications. It is an indirect additive used in food contact substances. … Other fatty acids contained in linseed oil include palmitic acid, stearic acid, oleic acid and linolenic acid.

  8. Drug

    Plozalizumab

    go.drugbank.com/drugs/DB12520
    Investigational

    Preclinical studies suggest that CCR2 plays an important role in the trafficking of monocytes and macrophages to sites of inflammation. … The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis.

  9. Drug

    Rexlemestrocel-L

    go.drugbank.com/drugs/DB17606
    Investigational

    It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial infarction. … Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product.

  10. Drug

    SN-38

    go.drugbank.com/drugs/DB05482
    Investigational

    SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others. … 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer