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Nedosiran
go.drugbank.com/drugs/DB17635ApprovedInvestigationalNedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate.
Flunixin
go.drugbank.com/drugs/DB11518ExperimentalVet approvedFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form. … Flunixin is regulated in the United States by the Food and Drug Administration (FDA) and must be prescribed by a licensed veterinarian.
Epratuzumab
go.drugbank.com/drugs/DB04958InvestigationalEpratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). … This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.
Bentracimab
go.drugbank.com/drugs/DB16659InvestigationalBentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-threatening Bleeding or Requiring Urgent Surgery or
Lobeline
go.drugbank.com/drugs/DB05137InvestigationalIt has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem]
Cinolazepam
go.drugbank.com/drugs/DB01594InvestigationalCinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
PD-0299685
go.drugbank.com/drugs/DB15264InvestigationalPD-0299685 is under investigation in clinical trial NCT00314964 (Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause).
KT-A261
go.drugbank.com/drugs/DB19317ExperimentalIt is being investigated for the treatment of noninfectious uveitis.
Bifidobacterium Longum Infantis 35624
go.drugbank.com/drugs/DB17871ExperimentalBifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]
ALKS 27
go.drugbank.com/drugs/DB05752ExperimentalStudy showed that ALKS 27 was well-tolerated over a wide dose range, with no dose-limited effects observed. … ALKS 27 is an inhaled formulation of trospium chloride for the treatment of chronic obstructive pulmonary disease (COPD).