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PEG-uricase
go.drugbank.com/drugs/DB05321InvestigationalPEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment
Tezosentan
go.drugbank.com/drugs/DB06558InvestigationalTezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events. … Tezosentan is an intravenous endothelin receptor A/B antagonist.
V-SARS
go.drugbank.com/drugs/DB15812Investigational[COVID-19 convalescent plasma] is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus. … Immunitor Inc., the sponsor, is currently testing this oral vaccine for immunogenicity in 20 healthy volunteers in a Phase 1 clinical trial (NCT04380532).
SAR445136
go.drugbank.com/drugs/DB17708Investigational[A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148]
Relamorelin
go.drugbank.com/drugs/DB12678InvestigationalRelamorelin has been investigated for the treatment and basic science of Gastroparesis, Gastric Motility, Diabetes Mellitus, Parkinson's Disease, and Chronic Constipation, among others.
Autologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
BAX 335
go.drugbank.com/drugs/DB17845InvestigationalBAX 335 is an adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of hemophilia B.[A259791]
TRK-001
go.drugbank.com/drugs/DB18577InvestigationalIt is being investigated for the prevention of graft rejection following solid organ transplantation.
Dithiopyr
go.drugbank.com/drugs/DB15230InvestigationalDithiopyr is under investigation in clinical trial NCT01236781 (Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates).