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Displaying results 41 - 50 of 9738 in total
  1. Drug

    Efprezimod alfa

    go.drugbank.com/drugs/DB16448
    Investigational

    CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.

    Synonyms: Human CD24 and human IgG Fc Fusion Protein
  2. Drug

    Givastomig

    go.drugbank.com/drugs/DB18618
    Investigational

    Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.

    Synonyms: an anti-Claudin 18.2 and 4.1BB Bispecific Antibody
  3. Drug

    RP-72

    go.drugbank.com/drugs/DB17156
    Investigational

    Synonyms: CXC chemokine receptor types 1 and 2 inhibitor RP72, 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin-8
  4. Drug

    PMC-403

    go.drugbank.com/drugs/DB18132
    Investigational

    PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.

    Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptor
  5. Drug

    TSHA-101

    go.drugbank.com/drugs/DB18280
    Investigational

    Synonyms: adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB
  6. Drug

    Elapegademase

    go.drugbank.com/drugs/DB14712
    Approved

    group in alanine and lysine residues. … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on October 5, 2018.[L4654,F1939]

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH, AN AVERAGE OFAPPROXIMATELY 13 .OMEGA.
  7. Drug

    MM-111

    go.drugbank.com/drugs/DB17983
    Investigational

    MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Antibody bispecific for erbb2 and erbb3
  8. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    [L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  9. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene
  10. Drug

    Romilkimab

    go.drugbank.com/drugs/DB16318
    Investigational

    Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).

    Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)