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Displaying results 41 - 50 of 7399 in total
  1. Drug

    Obexelimab

    go.drugbank.com/drugs/DB15032
    Investigational

    Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

    Synonyms: XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD OVER NATIVE IGG) TO FCGRIIB), humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb
  2. Drug

    KRN-330

    go.drugbank.com/drugs/DB19075
    Investigational

    Anti-a33 fully-human monoclonal antibody is under investigation in clinical trial NCT00838578 (Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer).

    Synonyms: HUMAN MONOCLONAL ANTIBODY TO COLON CANCER ANTIGEN A33
  3. Drug

    Nalotimagene carmaleucel

    go.drugbank.com/drugs/DB19155
    Investigational

    Synonyms: Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from Mo, HSV-TK
  4. Drug

    INZ-701

    go.drugbank.com/drugs/DB17629
    Investigational

    INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.

    Synonyms: Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 (INZ-701)
  5. Drug

    Labetuzumab

    go.drugbank.com/drugs/DB05097
    Investigational

    Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.

    Synonyms: MN14 monoclonal antibody to carcinoembryonic antigen
  6. Drug

    GTA002

    go.drugbank.com/drugs/DB17187
    Investigational

    Synonyms: Allogeneic ex-vivo generated CD56+CD3-natural killer cells from CD34+ umbilical cord blood progenitor cells, Allogeneic UCB-NK cells
  7. Drug

    CVac

    go.drugbank.com/drugs/DB17351
    Experimental

    Synonyms: Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase) coupled to oxidized polymannose
  8. Drug

    VO659

    go.drugbank.com/drugs/DB18160
    Investigational

    VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.

    Synonyms: an antisense oligonucleotide that has been developed to target expanded CAG repeats in messenger ribonucleic acid (mRNA)
  9. Drug

    Yeast beta-D-glucan

    go.drugbank.com/drugs/DB19271
    Investigational

    Yeast beta-D-glucan is under investigation in clinical trial NCT00632008 (Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers).

    Synonyms: -glucan from saccharomyces cerevisiae, Microparticulate beta-(1,3)(1,6) glucan from saccharomyces cerevisiae
  10. Drug

    QXL138AM

    go.drugbank.com/drugs/DB18552
    Investigational

    QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.

    Synonyms: Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a