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Displaying results 491 - 500 of 10000 in total
  1. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). … [A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Mar-venlafaxine XR, VENLAVITAE® 75 MG CÁPSULAS DURAS DE LIBERACIÓN PROLONGADA
  2. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

    Mixtures: REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET, REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Ephedra sinica stem

    go.drugbank.com/drugs/DB14747
    Investigational

    Synonyms: Cao ma huang, Ephedra ma-huang stem
  4. Drug

    AF-710B

    go.drugbank.com/drugs/DB16911
    Investigational

    Synonyms: 1-(2,8-dimethyl-1-thia-3,8-diazaspiro(4.5)dec-3-yl)-3-(1h-indol-3-yl)propan-1-one, 1-(2,8-Dimethyl-1-Thia-3,8-Diazaspiro[4.5]Dec-3-yl)-3-(1H-Indol-3-yl)Propan-1-one
  5. Drug

    Balsam of Peru

    go.drugbank.com/drugs/DB11482
    ApprovedNutraceuticalVet approved

    [F117] Under the FDA, balsam of Peru is considered as an inactive ingredient to be used for approved drug products[L2878] as well as an approved food additive under the categorization of generally recognized … Balsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676].

    Mixtures: Arnica De LA Abuela, DERIVERIN MERHEM, 25 GCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    Disorder (SAD), and as an aid for smoking cessation. … [L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically significant weight loss, with a mean change in body weight of -6.3% compared to -1.3% for placebo

    Mixtures: Appbutamone-DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  7. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat … a wide variety of infections.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas B
  8. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol, PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)-
  9. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection. … It is currently marketed under the trademark TEMODAR® by Merck.[L32033]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
  10. Drug

    Capsicum oleoresin

    go.drugbank.com/drugs/DB11131
    Approved

    Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. … Capsicum oleoresin is contained in pepper sprays when suspended in water, and acts an active lachrymatory agent that induces irritation, lacrimation, pain, and temporary blindness when in contact with

    Mixtures: HO YAN HOR MEDICATED OIL, SLOAN`S ANALGESIC RUB