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Zinpentraxin alfa
go.drugbank.com/drugs/DB14852InvestigationalZinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. … It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Synonyms: rhPTX-2, Recombinant human pentraxin-2Remetinostat
go.drugbank.com/drugs/DB14869InvestigationalRemetinostat is under investigation in clinical trial NCT02213861 (Efficacy, Safety and Tolerability Study of SHAPE in IA, IB or IIA Cutaneous T-cell Lymphoma).
AZD-4017
go.drugbank.com/drugs/DB14875InvestigationalAZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Categories: Heterocyclic Compounds, 1-Ring, 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitorsCEP-9722
go.drugbank.com/drugs/DB14882InvestigationalCEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingLorecivivint
go.drugbank.com/drugs/DB14883InvestigationalLorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPF-05180999
go.drugbank.com/drugs/DB14885InvestigationalPF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability of a Modified-Release Formulation of PF-05180999).
Vobarilizumab
go.drugbank.com/drugs/DB14891InvestigationalVobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers).
Galicaftor
go.drugbank.com/drugs/DB14894InvestigationalGalicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingVibegron
go.drugbank.com/drugs/DB14895ApprovedInvestigationalVibegron is a potent, selective beta-3 adrenergic receptor (β3) agonist that relaxes the detrusor smooth muscle of the bladder, thereby increasing bladder capacity. … [L28310] Vibegron is the second beta-3 adrenergic agonist approved for the treatment of overactive bladder following [mirabegron], which was approved in 2012.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesISO-1 F-18
go.drugbank.com/drugs/DB14900InvestigationalISO-1 F-18 is under investigation in clinical trial NCT00968656 (Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1).
Synonyms: F-18-ISO, [18F]ISO-1