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Rocatinlimab
go.drugbank.com/drugs/DB18809InvestigationalIn clinical trials, it has shown significant efficacy and safety compared to a placebo. … Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis.
ABG-023
go.drugbank.com/drugs/DB18829ExperimentalABG-023 is a glucagon analog which is soluble and solution-stable.[L50778]
Ziltivekimab
go.drugbank.com/drugs/DB18836InvestigationalZiltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Synonyms: Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal 2e2.3a9.6a3 .gamma.1-chain), disulfide with human monoclonal 2e2.3a9.6a3 .kappa.Allitinib
go.drugbank.com/drugs/DB18840ExperimentalAllitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of Anlotinib Combined With Allitinib in Lung Cancer).
Synonyms: 2-propenamide, n-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, N-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-2-propenamideCategories: Heterocyclic Compounds, 2-RingSocazolimab
go.drugbank.com/drugs/DB18845InvestigationalSocazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).
Synonyms: Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), disulfide with human monoclonal zkab001 .lambda.-chain, dimerDepemokimab
go.drugbank.com/drugs/DB18846ApprovedInvestigational[A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment. … Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug.
Categories: Interleukin-5 AntagonistSynonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimerRosnilimab
go.drugbank.com/drugs/DB18851InvestigationalRosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).
Synonyms: Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa.-chain, dimerNofazinlimab
go.drugbank.com/drugs/DB18852InvestigationalNofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Synonyms: Recombinant pd-1 mab cs1003, Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa.Etigilimab
go.drugbank.com/drugs/DB18854InvestigationalEtigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32Povorcitinib
go.drugbank.com/drugs/DB18855InvestigationalPovorcitinib is under investigation in clinical trial NCT06113445 (A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)).