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1,2-Benzodiazepine
go.drugbank.com/drugs/DB12537ApprovedInvestigationalWithdrawnBenzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease.
Hydroxydione
go.drugbank.com/drugs/DB08956ApprovedWithdrawnHydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.
Propanidid
go.drugbank.com/drugs/DB13234ExperimentalAn intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
Avena sativa flowering top
go.drugbank.com/drugs/DB14253ApprovedAvena sativa flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mupadolimab
go.drugbank.com/drugs/DB16488InvestigationalCPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy. … NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer).
Oportuzumab monatox
go.drugbank.com/drugs/DB05319InvestigationalVB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor cell-associated target highly expressed on carcinoma cells of epithelial origin … VB4-845 is studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells.
Imetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigational[A187838] Imetelstat received FDA approval in June 2024 for use in certain patients with MDS who have transfusion-dependent anemia and are unable to use ESAs.[L50883,L50888] … Imetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase.
Pumosetrag
go.drugbank.com/drugs/DB12402InvestigationalPumosetrag has been used in trials studying Gastroesophageal Reflux Disease.