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Cytochrome P450 1A Subfamily
go.drugbank.com/bio_entities/BE0010229TargetHumansMay act as a major enzyme for all-trans retinoic acid biosynthesis in the liver. … May act as a major enzyme for all-trans retinoic acid biosynthesis in extrahepatic tissues.
Synonyms: Cytochrome P450 form 6AVX-001
go.drugbank.com/drugs/DB19194InvestigationalAVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult
Sulfametrole
go.drugbank.com/drugs/DB15975InvestigationalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTolciclate
go.drugbank.com/drugs/DB13360ExperimentalCategories: Antifungals for Topical Use, Antifungals for Dermatological UseRozrolimupab
go.drugbank.com/drugs/DB05209InvestigationalRozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic
NM-702
go.drugbank.com/drugs/DB05505InvestigationalNissan Chemical and Taisho have been jointly developing NM-702, a drug for the treatment of arteriosclerosis obliterans. … In the USA, a Phase 2 study for intermittent claudication caused by arteriosclerosis obliterans has been successfully completed.
Bevirimat
go.drugbank.com/drugs/DB06581InvestigationalBevirimat, also known as PA-457 or YK-FH312, is investigated in clinical trials for treating HIV infection. Bevirimat is a solid.
Synephrine
go.drugbank.com/drugs/DB09203InvestigationalIt is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine. … The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine.
Sitimagene ceradenovec
go.drugbank.com/drugs/DB04907ExperimentalSitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy
BAX 335
go.drugbank.com/drugs/DB17845InvestigationalBAX 335 is an adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of hemophilia B.[A259791]