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Displaying results 501 - 510 of 10000 in total
  1. Drug

    Tolcapone

    go.drugbank.com/drugs/DB00323
    ApprovedInvestigationalWithdrawn

    Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. … It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenone
  2. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.

    Mixtures: Innoprax-5Categories: GABA-B Receptor Agonists
  3. Drug

    4-Hydroxytestosterone

    go.drugbank.com/drugs/DB01485
    IllicitInvestigational

    [A14385] Like formestane, 4-hydroxytesterone has been patented for use in decreasing estrogen production in the body, but no such indication currently exists. 4-Hydroxytestosterone was first patented in … Formestane (Lentaron) acts as a prohormone of 4-Hydroxytestosterone, as 4-Hydroxytestosterone is one of the many byproducts of formestane metabolism.

    Synonyms: 4-Androstene-7alpha-17beta-diol-3-one, 4,17beta-Dihydroxy-4-androstene-3-one
  4. Drug

    4-Phenylfentanyl

    go.drugbank.com/drugs/DB09168
    ExperimentalIllicit

    4-Phenylfentanyl is a sythetic opioid derived from fentanyl. 4-Phenylfentanyl is around 8x the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted … thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.

    Synonyms: N-(1-Phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide, 4-Phenylfentanyl
  5. Drug

    4-Methoxyamphetamine

    go.drugbank.com/drugs/DB01472
    ExperimentalIllicit

    Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: Formoterol fumarate related compound G, (2RS)-1-(4-methoxyphenyl)propan-2-amine
  6. Drug

    Dalosirvat

    go.drugbank.com/drugs/DB18960
    Investigational

    Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).

    Synonyms: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-butane-1,4-dione, 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione
  7. Drug

    4-Methylaminorex

    go.drugbank.com/drugs/DB01447
    ExperimentalIllicit

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Methylaminorex
  8. Drug

    4-Flourobenzenesulfonamide

    go.drugbank.com/drugs/DB01784
    Experimental

    Synonyms: 4-Flourobenzenesulfonamide
  9. Drug

    4-methoxybenzenesulfinate

    go.drugbank.com/drugs/DB03033
    Experimental

    Synonyms: 1-methyloxy-4-sulfone-benzene, 4-methoxybenzenesulfinate
  10. Drug

    4-Deoxyglucarate

    go.drugbank.com/drugs/DB03212
    Experimental

    Synonyms: 4-Deoxyglucarate