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Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Dexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalIt is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
LErafAON
go.drugbank.com/drugs/DB04973InvestigationalPhase I/II trials commenced in March 2001 and were ongoing as of June 2003.
Dihydrotachysterol
go.drugbank.com/drugs/DB01070ApprovedWithdrawnA vitamin D that can be regarded as a reduction product of vitamin D2.
Sulfameter
go.drugbank.com/drugs/DB06821ApprovedLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Mucor circinelloides f. lusitanicus
go.drugbank.com/drugs/DB15525ApprovedMucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Coffea arabica seed, roasted
go.drugbank.com/drugs/DB15603ApprovedCoffea arabica seed, roasted allergenic extract is used in allergenic testing.
Otenabant
go.drugbank.com/drugs/DB11745InvestigationalOtenabant has been investigated for the treatment of Obesity.
Pozanicline
go.drugbank.com/drugs/DB05458InvestigationalIn radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR subtypes.
Ciglitazone
go.drugbank.com/drugs/DB09201ExperimentalCiglitazone is a potent and selective PPARγ ligand with an EC50 of 3.0 µM. It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo. … Ciglitazone significantly decreases VEGF production by human granulosa cells in an in vitro study, and may potentially be used in ovarian hyperstimulation syndrome.