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Displaying results 5111 - 5120 of 10000 in total
  1. Drug

    Alfimeprase

    go.drugbank.com/drugs/DB04919
    Investigational

    It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo. … Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (<i>Agkistrodon contortrix contortrix</i>).

    Synonyms: 3-203-FIBROLASE (3-SERINE) (AGKISTRODON CONTORTRIX CONTORTRIX RECOMBINANT)
  2. Drug

    cryopreserved human liver cells

    go.drugbank.com/drugs/DB05852
    Experimental

    Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. … The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation

  3. Drug

    Spermine

    go.drugbank.com/drugs/DB00127
    InvestigationalNutraceutical

    Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. … Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species.

    Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamine
  4. Drug

    Iocarmic acid

    go.drugbank.com/drugs/DB13755
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated
  5. Drug

    Rocaglamide

    go.drugbank.com/drugs/DB15495
    Experimental

    [A186796] Reports of _Aglaia_ anti-tumor activity date back as far as 1973, and rocaglamide-A was first isolated in 1982 from the species _A. elliptifolia_. … Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Trimoprostil

    go.drugbank.com/drugs/DB19935
    Experimental

    Trimoprostil is a small molecule drug. The usage of the INN stem '-prostil' in the name indicates that Trimoprostil is a anti-ulcer prostaglandin. … Trimoprostil has a monoisotopic molecular weight of 378.28 Da.

    Categories: Prostaglandins E
  7. Drug

    Butyrfentanyl

    go.drugbank.com/drugs/DB09173
    ExperimentalIllicit

    [L7811] This compound is a schedule I controlled substance in the USA because it is a positional isomer of 3-Methylfentanyl. … [A182054] It is an analog of [fentanyl] with roughly 1/30 the potency.[L7811] Butyrfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  8. Drug

    Terevalefim

    go.drugbank.com/drugs/DB16397
    Investigational

    Terevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Tezacitabine

    go.drugbank.com/drugs/DB06433
    Investigational

    A synthetic purine nucleoside analogue with potential antineoplastic activity.

    Synonyms: 2'-Deoxy-2'-(fluoromethylene)cytidineCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    NM-702

    go.drugbank.com/drugs/DB05505
    Investigational

    In the USA, a Phase 2 study for intermittent claudication caused by arteriosclerosis obliterans has been successfully completed. … It is estimated that about 6 million people suffer from intermittent claudication in the USA, with only 10 percent of these people currently receiving treatment.

    Categories: Heterocyclic Compounds, 1-Ring