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Asimadoline
go.drugbank.com/drugs/DB05104InvestigationalAsimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis.
Ibritumomab tiuxetan
go.drugbank.com/drugs/DB00078ApprovedIbritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
NGX267
go.drugbank.com/drugs/DB05152InvestigationalIt is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Lenvatinib
go.drugbank.com/drugs/DB09078ApprovedInvestigationalLenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular functions, including fibroblast growth … However, for patients with RAI-refractory thyroid cancer, treatment options are limited and the prognosis is poor, leading to a push for the development of more targeted therapies such as lenvatinib.
Trifluoroethanol
go.drugbank.com/drugs/DB03226ExperimentalA non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.
Diloxanide furoate
go.drugbank.com/drugs/DB14638ApprovedInvestigationalSynonyms: 2,2-dichloroacetamido-4-n-methylphenyl 2-furoate, 4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoateVLTS-934
go.drugbank.com/drugs/DB05597InvestigationalIt was under investigation in clinical trial NCT00113009 (Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease). … VLTS-934 was developed by Valentis inc. for the treatment of Peripheral Arterial Disease (PAD).
Recombinant Human Thrombopoietin
go.drugbank.com/drugs/DB16364InvestigationalRecombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary cells and is used to promote the generation of megakaryocytes and platelets.
MIP-1095 I-123
go.drugbank.com/drugs/DB12994Experimental123 I Mip 1095 is under investigation in clinical trial NCT00712829 (Study to Evaluate the Safety, Pharmacokinetics, Tissue Distribution, Metabolism and Dosimetry of Two Prostate Cancer Imaging Agents)
D-arginine
go.drugbank.com/drugs/DB04027ExperimentalA D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).