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Ramucirumab
go.drugbank.com/drugs/DB05578ApprovedInvestigationalBy binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation,
Faropenem medoxomil
go.drugbank.com/drugs/DB05659InvestigationalFaropenem medoxomil is an ester prodrug derivative of the beta-lactam antibiotic faropenem. The prodrug form of faropenem offers dramatically improved oral bioavailability and leads to higher systemic concentrations of the drug. Faropene...
Prolectin-M
go.drugbank.com/drugs/DB16521InvestigationalProlectin-M is a (1-6)-alpha-D-mannopyranose[L31338] and acts as an antagonist of galectin.
BCX10013
go.drugbank.com/drugs/DB18496InvestigationalBCX10013 is a small molecule inhibitor of human complement factor D.
Zelpultide alfa
go.drugbank.com/drugs/DB18587InvestigationalZelpultide alfa is a recombinant human surfactant protein D.
Synonyms: RECOMBINANT SP-D, HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS,CL-315585
go.drugbank.com/drugs/DB18758ExperimentalCL-315585 is the D isomer of [Verteporfin].
Synonyms: Bpd-ma(sub d), Verteporfin d isomerGW-468816
go.drugbank.com/drugs/DB15099ExperimentalGW-468816 is under investigation in clinical trial NCT00218465 (Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking).
Categories: Receptors, N-Methyl-D-Aspartate, antagonists & inhibitorsLeptazoline A
go.drugbank.com/drugs/DB15551ExperimentalAlso see [Leptazoline B], [Leptazoline C], and [Leptazoline D].
Leptazoline B
go.drugbank.com/drugs/DB15552ExperimentalAlso see [Leptazoline A], [Leptazoline C], and [Leptazoline D].