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Sipagladenant
go.drugbank.com/drugs/DB17080InvestigationalKW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]
Tinlorafenib
go.drugbank.com/drugs/DB17082InvestigationalTinlorafenib (PF-07284890) is a potent, selective, highly brain-penetrant, small-molecule inhibitor of BRAF V600 mutations.[A253992]
Gadopiclenol
go.drugbank.com/drugs/DB17084ApprovedInvestigationalGadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. … [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at lower doses than classic extracellular GBCAs.
KDT-3594
go.drugbank.com/drugs/DB17085InvestigationalKDT-3594 is a non-ergot dopamine receptor agonist developed by Kissei Pharmaceutical.
UCB7362
go.drugbank.com/drugs/DB17096Experimental[A254232] UCB7362 is estimated to achieve a significant reduction in asexual blood-stage parasites.
Briquilimab
go.drugbank.com/drugs/DB18136InvestigationalBriquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
ATX-01
go.drugbank.com/drugs/DB18141InvestigationalATX-01 is an antimiR, a chemically modified antisense oligonucleotide, designed to target microRNA 23b (miR-23b).
MTL-CEBPA
go.drugbank.com/drugs/DB18143InvestigationalMTL-CEBPA is a SMARTICLES liposomal formulation of MTL-501, a small activating RNA (saRNA) oligonucleotide.
BRG01
go.drugbank.com/drugs/DB18173InvestigationalBRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.[L48111]
Etavopivat
go.drugbank.com/drugs/DB18176InvestigationalEtavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.